Effect of combined lateral and supine positioning on oxygen saturation in ICU patients during the mechanical ventilator weaning process: A randomized controlled trial

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Effect of combined lateral and supine positioning on oxygen saturation in ICU patients during the mechanical ventilator weaning process: A randomized controlled trial

Purnawan, Iwan - Personal Name; Hidayat, Arif Imam - Personal Name; Alivian, Galih Noor - Personal Name; Wirakhmi, Ikit Netra - Personal Name; Awaludin, Sidik - Personal Name; Susetya, Putut Anggara - Personal Name; Chanshintop, Sawinee - Personal Name;

Background: Prolonged mechanical ventilation in ICU patients increases mortality risk and length of stay. Ineffective weaning can exacerbate the patient’s condition and further elevate mortality risk due to hypoxemia-induced cellular damage, contributing to ICU overcrowding.Purpose: This study investigates the effect of lateral positioning on oxygen saturation in ICU patients undergoing mechanical ventilator weaning.Methods: A randomized controlled trial (RCT) with block randomization was conducted, enrolling 60 participants assigned to either the intervention group (n = 30) or the control group (n = 30). The intervention group received 5% FiO2 and was repositioned every two hours (right lateral, supine, left lateral), whereas the control group remained supine with 5% FiO2. Oxygen saturation (SaO2) was measured using pulse oximetry before and after the intervention. As the data were not normally distributed, the Mann-Whitney U test was used to compare SaO2 changes between groups, with statistical significance set at p < 0.05.Results: Baseline characteristics, including age, gender, and ventilator duration, were comparable between groups (p > 0.05). The median increase in SaO2 was 6% (IQR: 1–8%) in the intervention group and 1% (IQR: 0–3%) in the control group, with a significant between-group difference of 5% (p < 0.001). A large effect size (η² = 0.68) indicated a substantial impact of lateral positioning on SaO2.Conclusions: Lateral positioning significantly improves oxygen saturation in ICU patients undergoing ventilator weaning, potentially reducing complications associated with prolonged mechanical ventilation.

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Series Title: Jurnal Keperawatan Padjadjaran, Vol. 13 Issue 1 April 2025
Call Number: (05) 610.5 FAK j
Publisher: Sumedang : Fakultas Keperawatan UNPAD., 2025
Collation: Hlm. 26-34
Language: English
ISBN/ISSN: 1410-4490
Classification: (05) 610.5 FAK j
Content Type: -
Media Type: -
Carrier Type: -
Edition: Vol. 13 Issue 1 April 2025
Subject(s): Mechanical ventilation
Critical Patients
Lateral Position
Oxygen Saturation
Specific Detail Info: -
Statement of Responsibility: -

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Jurnal Keperawatan Padjadjaran, Vol. 13 Issue 1 April 2025

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